[HTML][HTML] Neuroprotective effects of doxycycline in the R6/2 mouse model of Huntington's disease
E Paldino, C Balducci, P La Vitola, L Artioli… - Molecular …, 2020 - Springer
… ), the administration of minocycline was associated with the delay of disease progression.
In … huntingtin by minocycline and doxycycline was not associated with beneficial effects in …
In … huntingtin by minocycline and doxycycline was not associated with beneficial effects in …
Minocycline and doxycycline: more than antibiotics
S Singh, D Khanna, S Kalra - Current Molecular Pharmacology, 2021 - ingentaconnect.com
… and pyruvate treatment reversed the neuronal insult produced by striatal injection of
quinolinic acid, an excito-toxic animal model of Huntington's disease. Inflammatory responses …
quinolinic acid, an excito-toxic animal model of Huntington's disease. Inflammatory responses …
Cytotoxicity models of Huntington's disease and relevance of hormetic mechanisms: A critical assessment of experimental approaches and strategies
… This paper assesses in vivo cytotoxicity models of Huntington’s disease (HD). Nearly 150 …
cytotoxic induction of HD features in multiple rodent models. Typically, rodents are treated with …
cytotoxic induction of HD features in multiple rodent models. Typically, rodents are treated with …
Repurposing of Minocycline, a Tetracycline Antibiotic, for Neurodegenerative Disorders
RB Sanshita, P Sood, D Thakur, A Kuhad - … Emerging Infectious Diseases …, 2023 - Springer
… Alzheimer’s disease, Huntington's disease, Parkinson’s disease, Amyotrophic lateral …
effect of minocycline in several models of acute and chronic neurodegenerative disease like …
effect of minocycline in several models of acute and chronic neurodegenerative disease like …
[HTML][HTML] The therapeutic role of minocycline in Parkinson's disease
… readily crosses the blood-brain barrier with a rate of at least fivefold higher than doxycycline…
In one MPTP model, minocycline treatment blocked dopamine depletion in the nucleus …
In one MPTP model, minocycline treatment blocked dopamine depletion in the nucleus …
Challenges of repurposing tetracyclines for the treatment of Alzheimer's and Parkinson's disease
I Markulin, M Matasin, VE Turk… - Journal of Neural …, 2022 - Springer
… The research in animal AD/PD models provided evidence on … The neuroprotective effects
of minocycline and doxycycline … a long-standing doxycycline and minocycline therapy in these …
of minocycline and doxycycline … a long-standing doxycycline and minocycline therapy in these …
The mechanisms underlying minocycline non-antibiotic effects
GJA Fernandes - 2022 - repositorio.ul.pt
… This effect has been confirmed in experimental models of … including Parkinson's disease,
Huntington's disease, amyotrophic … as antibiotics are doxycycline and minocycline, which are …
Huntington's disease, amyotrophic … as antibiotics are doxycycline and minocycline, which are …
[HTML][HTML] The potential use of tetracyclines in neurodegenerative diseases and the role of nano-based drug delivery systems
M Rahmani, SEN Álvarez, EB Hernández - European Journal of …, 2022 - Elsevier
… neuroprotective roles of minocycline and doxycycline in four … neurodegenerative disorders
(ALS, Huntington's disease, PD… In most CNS models the dose of minocycline required to …
(ALS, Huntington's disease, PD… In most CNS models the dose of minocycline required to …
Minocycline in neurological disorders treatment
CQC Leite - 2021 - repositorio.ul.pt
… , with doxycycline taking its place and minocycline being currently … diseases and rheumatoid
arthritis. Among tetracyclines, … In an EAE animal model, minocycline reduced Tumor …
arthritis. Among tetracyclines, … In an EAE animal model, minocycline reduced Tumor …
Tetracyclines for Prevention and Treatment of Nervous System Disorders
CAG Rocha - 2020 - search.proquest.com
… absorption of minocycline and doxycycline does not appear … (12), although, oral doxycycline
and minocycline must be taken … pathways in models of Huntington's disease. Proceedings of …
and minocycline must be taken … pathways in models of Huntington's disease. Proceedings of …